Surget and colleagues findings suggest that neurogenesis may cause interference CRF1 receptor antagonist as effective in the treatment of stress-related behavioral disturbances even in a context where other antidepressants do not work.
Results from trials of antidepressant drugs in recent years were mixed and Alexandre Surget And colleagues ask whether it is time to give corticotropin-releasing factor-1 antagonist as antidepressants – those that recently failed in a large clinical trial – or the time the agents the agents from a different perspective. It became known down-regulation anxiety disorders linked to dysfunction of the hypothalamic-pituitary – adrenal axis and structural changes in the hippocampus itself. Animal studies in mice have shown that unpredictable chronic mild stress can ignite these effects and UCMS – induced changes. Including down-regulation of neurogenesis – antidepressant treatment reversed Knowing that stress-related disorders of neurogenesis can be reversed is important.Apart Chevrier and Eskenazi authors of the paper Kim G. Asa Bradman, Myriam Gharbi and Andrew Sj are with DIN? by grants from by grants from the U.S. Environmental Protection Agency and National Institute of Environmental Health Sciences. Additional funding were provided at the University of California Institute on Mexico and the State .
U.S. Consumer about thyroid hormones in pregnancy linked.
Chevrier and colleagues worked with a group from 270 women who recruited between 1999 to 2000 at the Center for the Health Assessment maternal and Children of Salinas attend study if they were pregnant. Most of of the attendees were Mexican American.