From 8554 patients who suffered pioglitazone, 4.4 percent of them had a heart attack, stroke or death, compared with 5 click to see full text .7 percent of the 7,836 therapy treated with control therapy – ie a reduction of 18 percent. However, had 2.3 percent of patients compared with 1.8 percentserious heart failure, compared with 1.8 percent in the control group. – The authors declare, ‘These results indicate that the net clinical cardiovascular benefit with pioglitazone therapy is favorable, with a significant reduction in irreversible ischemic events that is not attenuated by the risk of more frequent heart failure complications. ‘ – ‘Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus – A meta – analysis of randomized trials ‘A. Michael Lincoff, MD, Kathy Wolski, MPH, Stephen J. Nicholls, PhD, Steven E. MD JAMA. 2007, 298:1180-1188. Click here.
Wyeth Pharmaceuticals supported the study.The American Academy of Neurology, an association of more than 20,000 neurologists and neuroscience professionals , improving patient care through education and research is dedicated. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as stroke, Alzheimer’s disease, epilepsy, Parkinson’s disease and multiple sclerosis.
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